Acne clinical trials
Medical name: Acne vulgaris · Skin
By location or age: Children and teens · California · Florida · Kentucky · Michigan
89 trials are recruiting, according to ClinicalTrials.gov.
Checked against the registry on 5 October 2026. Listing a trial here is not a recommendation; taking part is voluntary and each study team decides who is eligible.
Study to Assess Safety, Pharmacokinetics, and Treatment Effect of Cabtreo
Ages 9 Years to 11 Years · 15 sites · Bausch Health Americas, Inc.
Details and how to check if you qualify · NCT07524946 on ClinicalTrials.gov
Role of Akkermansia Muciniphila in Acne Vulgaris
Ages 18 Years to 45 Years · 0 sites · Medical University of South Carolina
Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or Obesity
Ages 18 Years to no maximum · 0 sites · Regeneron Pharmaceuticals
Safety of the Acne mRNA Vaccine in Adolescents 12 to 17 Years of Age With Moderate to Severe Acne
Ages 12 Years to 17 Years · 0 sites · Sanofi
Demodex Mites in Acne Patients and Herbal Extract Susceptibility
Ages 18 Years to 45 Years · 0 sites · Assiut University
Radiofrequency Treatment Versus Topical Therapy for Facial Acne Vulgaris
Ages 18 Years to 40 Years · 1 site · Jeisys Medical Inc
Dermal and Ophthalmological Acceptability and Comedogenicity Assessment of a Cosmetic Product
Ages 18 Years to 45 Years · 1 site · Brainfarma Industria Química e Farmacêutica S/A
Investigating the Efficacy of Oral Probiotics Versus Placebo in Pakistani Patients With Moderate Acne on Acne Lesion Count and Systemic Inflammation
Ages 15 Years to 35 Years · 1 site · Foundation University Islamabad
A Randomised Controlled Trial of ePROM-Guided Flexible Scheduling in Dermatology
Ages 16 Years to no maximum · 0 sites · National University Hospital, Singapore
Study of New Antiandrogenic Progestogen + Low-dose Estrogen for Moderate Acne Vulgaris
Ages 14 Years to 45 Years · 1 site · Eurofarma Laboratorios S.A.
Comparison of Topical Clascoterone and Adapalene for Mild Acne Vulgaris
Ages 12 Years to 35 Years · 0 sites · Khyber Teaching Hospital
Prevalence of Polyendocrine Metabolic Ovarian Syndrome in Patients Diagnosed With Acne Vulgaris in Sohag University Hospital
Ages 15 Years to 49 Years · 1 site · Sohag University
Photodynamic Therapy With Topical Application of a Zn(II) Phthalocyanine (RLP068/Cl) and Red Light for the Treatment of Moderate-to-severe Acne Vulgaris
Ages 16 Years to no maximum · 0 sites · Università degli Studi di Brescia
Clinical Observation of Skin Condition in Patients With Acne Vulgaris Using Ubiquinol, Pomegranate Peel Extract, Ceramide, and Salicylic Acid Emulsion
Ages 18 Years to 40 Years · 0 sites · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Low-Dose Versus Conventional-Dose Oral Isotretinoin for Acne Vulgaris
Ages 18 Years to 45 Years · 1 site · Pakistan Institute of Medical Sciences
A Clinical Trial to Investigate the Efficacy and Safety of GenLabs' Social Renew on Improving Acne Symptoms and Skin Repair Among Healthy Adults
Ages 18 Years to 65 Years · 1 site · GenCanna Acquisition Corp
Safety and Efficacy of Skincare Products for Managing Mild to Moderate Acne in Individuals With Sensitive Skin
Ages 18 Years to no maximum · 1 site · USMARI Research & Innovation Centre
Exploring Acne Treatments Through Clinical Research Participation
Ages 18 Years to no maximum · 1 site · Power Life Sciences Inc.
Safety and Efficacy Evaluation of the Radiofrequency Therapeutic Device for the Treatment of Atrophic Acne Scars
Ages 18 Years to 65 Years · 4 sites · CLASSYS Inc.
1% Clascoterone Cream for the Treatment Acne Vulgaris
Ages 12 Years to no maximum · 0 sites · Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd.
Efficacy and Safety of Combined Nanofat Injection With Either Platelet Rich Fibrin or Microneedling Versus Nanofat Injection Alone in the Treatment of Facial Atrophic Post Acne Scars
Ages 18 Years to 45 Years · 0 sites · Assiut University
Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial
Ages 40 Years to 60 Years · 1 site · King's College London
Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.
Ages 9 Years to no maximum · 1 site · Integrative Skin Science and Research
Comparative Effectiveness of Clindamycin-Retinoid, Clindamycin-Retinoid-Dexamethasone, and 10% SM-hUCMSC Secretome Gel in the Improvement of Mild-to-Moderate Acne Vulgaris
Ages 15 Years to 40 Years · 1 site · Yohanes Firmansyah, dr, MH, MM
Sebum Metabolomics and Lipidomics for Clinical Applications
Ages 20 Years to no maximum · 0 sites · National Taiwan University Hospital
Evaluation of Topical Dutasteride as a Potential New Therapy for Facial Acne Vulgaris Versus the Triple Combination Therapy (Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel)
Ages 18 Years to no maximum · 0 sites · Assiut University
Topical 5% Spironolactone Gel Versus 0.1% Adapalene Gel for Acne Vulgaris: A Randomized Split-Face Study
Ages 18 Years to 45 Years · 1 site · Assiut University
A Study to Evaluate Efficacy and Safety of HB0043 in Aadult Patients With Moderate to Severe Acne Vulgaris.
Ages 18 Years to no maximum · 1 site · Shanghai Huaota Biopharmaceutical Co., Ltd.
Poly-L-Lactic Acid in Atrophic Acne Scars
Ages 18 Years to 40 Years · 1 site · Zagazig University
Evaluation of Juläine (TM) for the Treatment of Atrophic Facial Acne Scars
Ages 18 Years to no maximum · 2 sites · Nordberg Medical AB
Efficacy of 0.5% Topical Timolol Eye Drops in the Treatment of Post-Inflammatory Erythema Following Acne Vulgaris
Ages 12 Years to no maximum · 1 site · Pham Ngoc Thach University of Medicine
Non-interventional Translational Study in Mild, Moderate and Severe Acne Patients
Ages 18 Years to 25 Years · 0 sites · National Skin Centre
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
Ages 12 Years to 17 Years · 30 sites · Incyte Corporation
Metronidazole 2% Gel Versus Clindamycin 1% Gel for Moderate Acne Vulgaris
Ages 18 Years to 35 Years · 0 sites · Jinnah Postgraduate Medical Centre
Efficacy and Tolerability of DispersinB Acne Cleanser in the Treatment of Mild to Moderate Acne Vulgaris
Ages 18 Years to no maximum · 1 site · Kane Biotech Inc
The Impact of Baseline Hormonal Profiles (DHEAS, FSH, LH) on Treatment Response to Systemic Isotretinoin in Adult Female Patients With Acne Vulgaris
Ages 18 Years to 40 Years · 1 site · Biruni University
Expert Consensus on the Use of Isotretinoin in Acne Vulgaris: A Delphi Study
Ages No minimum to no maximum · 1 site · Venus Research Center
Facial Skin Microbiome in Patients With Moderate-to-Severe Acne Vulgaris Treated With Isotretinoin
Ages 16 Years to 35 Years · 1 site · Can Tho University of Medicine and Pharmacy
Safety, Efficacy and Pharmacokinetic Characteristics of KR230109 Cream in Facial Acne Vulgaris
Ages 18 Years to 40 Years · 0 sites · Jiangxi Kvvit Pharmaceutical Co., Ltd.
Topical Application of Engineered Lactobacillus Reuteri With a Zinc Sulfate-Tannic Acid MPN Coating for Acne
Ages 18 Years to 33 Years · 1 site · Shenzhen People's Hospital
Comparison of the Clinical Efficacy and Safety of Topical and Subcutaneous Injection of Secukinumab in HS
Ages 18 Years to no maximum · 1 site · Peking Union Medical College
Comparative Real-world Study on Ablative Fractional CO₂ Laser vs PRP With Microneedling for Acne Scar Treatment.
Ages 18 Years to no maximum · 1 site · Dr. Sirajul Islam Medical College
Acne Face Wash for Reducing the Contamination Rate in Arthroscopic Rotator Cuff Repair Surgery
Ages 18 Years to no maximum · 1 site · National Taiwan University Hospital
Evaluation of Serum Ceramides C16, C24, and Sphingosine-1-Phosphate (S1P) in Patients With Acne Vulgaris
Ages 15 Years to 40 Years · 0 sites · Sohag University
Subcision With CO₂ Laser or PRP vs Subcision Alone in Atrophic Acne Scars
Ages 18 Years to no maximum · 1 site · Assiut University
PRP Plus Fractional CO₂ Laser for Acne Scars
Ages 18 Years to 40 Years · 1 site · Gujranwala medical college District Headquarters Hospital, Gujranwala
A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars
Ages 22 Years to no maximum · 10 sites · AbbVie
Subcision With Injection of Poly Deoxyribonucleotide Versus Subcision With Injection of Non-cross Linked Hyaluronic Acid in Rolling Acne Scars Treatment.
Ages 18 Years to no maximum · 1 site · Cairo University
Efficacy of Combined Fractional Er:Glass and Thulium Lasers Versus Microneedling for Atrophic Acne Scars
Ages 18 Years to 45 Years · 1 site · University of Nove de Julho
1726-nm Laser for Acne Inversa (Hidradenitis Suppurativa)
Ages 18 Years to 60 Years · 1 site · Wynn Medical Center
Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES
Ages 18 Years to 60 Years · 1 site · Dr.dr.Irma Bernadette, SpKK (K)
Correlation Between Acne Vulgaris and Lipid Profile Among Young Adults in Sohag Governorate
Ages 12 Years to 45 Years · 1 site · Sohag University
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
Ages 18 Years to no maximum · 8 sites · Leiden University Medical Center
Cold Atmospheric Plasma for Moderate-to-severe Acne Vulgaris Study
Ages 18 Years to 40 Years · 1 site · Shenyang Medical College
Efficacy and Safety of Adapalene Gel and Hyaluronic Acid Versus Adapalene Gel Alone in Mild to Moderate Acne Vulgaris
Ages No minimum to no maximum · 1 site · Badr University
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
Ages 18 Years to 45 Years · 4 sites · Sanofi Pasteur, a Sanofi Company
Phenytoin in Treatment of Atrophic Post Acne Scars.
Ages 18 Years to no maximum · 0 sites · Assiut University
Efficacy of Stromal Vascular Fraction on Acne Scar Correction
Ages 19 Years to 45 Years · 0 sites · Seoul National University Hospital
An Observational Clinical Study to Evaluate the Efficacy of the CeraVe Skin Care Line
Ages 13 Years to no maximum · 0 sites · ChinaNorm
PMCF Investigation of Medical Device ChitoCare® Medical
Ages No minimum to no maximum · 2 sites · Primex ehf
Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne
Ages 18 Years to 55 Years · 1 site · Sagimet Biosciences Inc.
Excimer Light Versus Blue Light in Acne
Ages 18 Years to 25 Years · 0 sites · Cairo University
Dry Eye Disease With Isotretinoin ISOTRETINOIN
Ages 18 Years to 40 Years · 0 sites · Cairo University
Efficacy of Dihydroartemisinin for Treating Acne Vulgaris
Ages 18 Years to 40 Years · 1 site · Shanghai Zhongshan Hospital
The Relationship Between Microbioma Balance and Acne Vulgaris as a New Acne Treatment
Ages 13 Years to 45 Years · 1 site · Universitas Padjadjaran
Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients
Ages 13 Years to 30 Years · 19 sites · Centre Hospitalier Universitaire de Nice
Comparison of Efficacy of 35% Glycolic Acid vs 20% Salicylic Acid Peel in the Treatment of Post Acne Scars
Ages 18 Years to 45 Years · 1 site · Hayatabad Medical Complex
Serum CXCL10 and CRP Levels in Patients With Acne Vulgaris in Correlation With Disease Severity
Ages 12 Years to 40 Years · 1 site · Assiut University
The Effectiveness and Safety of Cleanser Containing Triethyl Citrate, Pyruvic Acid, Combination Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic Acid and Spot Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Honokiol
Ages 15 Years to 50 Years · 1 site · Dr.dr.Irma Bernadette, SpKK (K)
Comparison of Efficacy of Microneedling With Platelet Rich Plasma Vs Microneedling With Topical Insulin in the Treatment of Acne Scars
Ages 18 Years to 50 Years · 1 site · Khyber Teaching Hospital
Weekly Isotretinoin vs Tetracycline for Moderate Acne
Ages 12 Years to no maximum · 1 site · Medical University of South Carolina
HS ABSCESSES: I&D VS PUNCH DEBRIDEMENT
Ages 16 Years to no maximum · 1 site · Erasmus Medical Center
Assessment of Serum Catestatin Level in Acne Vulgaris Patients
Ages 18 Years to 40 Years · 1 site · Aswan University
Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis
Ages 18 Years to 60 Years · 1 site · Nanjing First Hospital, Nanjing Medical University
Global Healthcare Study on Hidradenitis Suppurativa
Ages 14 Years to no maximum · 1 site · Julia Tatjana Maul
Various Procedural Treatment Options for Post-acne Atrophic Scars
Ages 13 Years to 50 Years · 1 site · Sheikh Zayed Medical College
Participants with Mild to Moderate Hidradenitis Suppurativa Will Receive EVO101 a Topical Cream 0.1%
Ages 18 Years to no maximum · 1 site · Virginia Clinical Research, Inc.
Fractional CO2 Laser Delivery of Topical Insulin Versus Platelet Rich Plasma in Treatment of Atrophic Post Acne Scars
Ages 18 Years to 65 Years · 0 sites · Assiut University
AVAVA MIRIA General Use
Ages 18 Years to 70 Years · 1 site · AVAVA, Inc.
A Comparative Study of Cosmetic Product in Subjects With Facial Acne During an Associated-treatment Phase Followed by a Maintenance Phase
Ages 14 Years to 24 Years · 1 site · Pierre Fabre Dermo Cosmetique
Efficacy and Safety of Clascoterone Cream 1% in Facial Acne Vulgaris
Ages 12 Years to no maximum · 1 site · Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd.
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Ages 18 Years to 45 Years · 94 sites · Sanofi Pasteur, a Sanofi Company
Intense Pulsed Light (IPL) Medical Device as Treatment for Patient Suffering From Skin Disorder
Ages 18 Years to no maximum · 5 sites · Eurofeedback
Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers
Ages 18 Years to no maximum · 1 site · Innovaderm Research Inc.
Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color
Ages 18 Years to no maximum · 1 site · Montefiore Medical Center
Efficacy and Safety of Secukinumab in Conjunction With Surgery in Moderate to Severe Hidradenitis Suppurativa
Ages No minimum to 80 Years · 1 site · Peking Union Medical College
Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital
Ages No minimum to no maximum · 1 site · Nantes University Hospital
Study to Evaluate the Efficacy of a Micro Coring Device for the Treatment of Scars of the Cytrellis Micro-Coring Device for the Treatment of Scars
Ages 18 Years to no maximum · 1 site · Cytrellis Biosystems, Inc.
Anti-inflammatory Effects of Topical Erythromycin and Clindamycin in Acne Patients
Ages 18 Years to 45 Years · 1 site · Centre for Human Drug Research, Netherlands
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