Alzheimer’s disease and related dementias clinical trials

Recruiting · Not applicable · Listed on Beacon

Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

Ages 65 Years to 90 Years · 2 sites · Hebrew SeniorLife

Details and how to check if you qualify · NCT06821568 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Advancing Ethical Goals In Society Trial

Ages 65 Years to no maximum · 2 sites · Tufts Medical Center

NCT07824245 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Web-Based Insomnia Treatment for Spousal Dementia Caregivers (SHUTi-DC)

Ages 18 Years to no maximum · 0 sites · University of Missouri-Columbia

NCT07836491 on ClinicalTrials.gov

Not yet recruiting · Not applicable

An Insole and Ankle Device for Monitoring Cognitive Decline in Individuals at Risk for Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD)

Ages 55 Years to no maximum · 1 site · HealthPartners Institute

NCT07127133 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Improv Music Therapy for Older Adults

Ages 60 Years to no maximum · 1 site · University of California, San Francisco

NCT07419022 on ClinicalTrials.gov

Not yet recruiting · Not applicable

A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social Engagement

Ages 18 Years to no maximum · 1 site · University of Minnesota

NCT07773493 on ClinicalTrials.gov

Not yet recruiting · Phase 3

To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)

Ages 18 Years to no maximum · 0 sites · Eidos Therapeutics, a BridgeBio company

NCT07116473 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Dyadic Life Review Intervention for Older Patients With Advanced Cancer and Alzheimer's Disease and Related Dementias and Their Caregivers

Ages 50 Years to no maximum · 1 site · University of Rochester

NCT07796347 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Cognition and Affective Research in China

Ages No minimum to no maximum · 1 site · Xuanwu Hospital, Beijing

NCT07833267 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Jigsawdio Multisensory Platform for People With Mild Cognitive Impairment, Alzheimer's Disease, or Related Dementias

Ages 60 Years to no maximum · 2 sites · Callahan-Young LLC DBA Jigsawdio

NCT07839286 on ClinicalTrials.gov

Not yet recruiting · Not applicable

GAPcareAD: A Brief Emergency Department Intervention to Address Post-Fall Care Needs of Persons Living With Dementia and Care Partners

Ages 65 Years to no maximum · 0 sites · University of Colorado, Denver

NCT07563270 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Probiotic Milk Drink for Gut and Brain Health in Older Adults and Caregivers

Ages 18 Years to no maximum · 1 site · University of South Florida

NCT07800195 on ClinicalTrials.gov

Not yet recruiting · Early Phase 1

Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.

Ages 55 Years to no maximum · 1 site · Noah Tech, Corp.

NCT07214974 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Remote Monitoring in Progressive Supranuclear Palsy (PSP)

Ages 18 Years to 89 Years · 2 sites · Massachusetts General Hospital

NCT04753320 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Veech Ketone Ester to Support Brain Energy in Mild Cognitive Impairment and Early Alzheimer's Disease

Ages 21 Years to no maximum · 1 site · University of Pennsylvania

NCT06767124 on ClinicalTrials.gov

Recruiting · Not applicable

Presence of Anti-RACH Antibodies and Neurocognitive Disorder in Myasthenic or Alzheimers's Patients.

Ages 18 Years to no maximum · 1 site · Centre Hospitalier Universitaire de Nice

NCT06523296 on ClinicalTrials.gov

Not yet recruiting · Not applicable

VICA: A Virtual Care Assistant for Dementia Caregivers

Ages 21 Years to no maximum · 1 site · Indiana University

NCT07779785 on ClinicalTrials.gov

Recruiting · Phase 4

Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis

Ages 18 Years to 80 Years · 1 site · Eidos Therapeutics, a BridgeBio company

NCT07695701 on ClinicalTrials.gov

Not yet recruiting · Not applicable

REPAIR Sleep Study

Ages 18 Years to no maximum · 0 sites · Emory University

NCT07572565 on ClinicalTrials.gov

Recruiting · Not applicable

Randomized Controlld Trial of Dementia Education Resources for Action

Ages 18 Years to no maximum · 1 site · George Mason University

NCT07545577 on ClinicalTrials.gov

Not yet recruiting · Not applicable

CommunityRx-Dementia + Peer Navigation (CRxDpeer)

Ages 18 Years to no maximum · 0 sites · University of Chicago

NCT07346183 on ClinicalTrials.gov

Not yet recruiting · Not applicable

High-Velocity Resistance Training for Brain Blood Flow and Cognitive Function in Older Adults

Ages 60 Years to 79 Years · 0 sites · University of Illinois at Chicago

NCT07444554 on ClinicalTrials.gov

Recruiting · Not applicable

Designing Care Management for Hospice Transitions for Persons Living With Advanced Dementia

Ages 18 Years to no maximum · 1 site · New York University

NCT07182357 on ClinicalTrials.gov

Recruiting · Not applicable

Financial Counseling for Dementia Family Caregivers in Early and Middle Adulthood

Ages 25 Years to 55 Years · 1 site · University of Utah

NCT07681401 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders

Ages 18 Years to no maximum · 1 site · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

NCT07239843 on ClinicalTrials.gov

Recruiting · Phase 3

Evaluate the Use of [18F]-APN-1607 PET in Subjects With AD-related Cognitive Impairment and Subjects With Normal Cognitive Function

Ages 50 Years to no maximum · 2 sites · JYAMS PET Research & Development Limited

NCT07422857 on ClinicalTrials.gov

Recruiting · Not applicable

Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study

Ages 55 Years to 89 Years · 1 site · Cedars-Sinai Medical Center

NCT07224607 on ClinicalTrials.gov

Recruiting · Not applicable

Positive Psychology for Early Cognitive Decline: Effects on Cognitive and Brain Function

Ages No minimum to no maximum · 1 site · Aristotle University Of Thessaloniki

NCT07289061 on ClinicalTrials.gov

Recruiting · Not applicable

Biofluid Research on Age-Related or Inherited Neurodegeneration

Ages 18 Years to no maximum · 1 site · University of Pennsylvania

NCT07798700 on ClinicalTrials.gov

Recruiting · Not applicable

Feasibility of Wearables in Dementia Care in Rural Taiwan

Ages No minimum to no maximum · 1 site · China Medical University Hospital

NCT07249918 on ClinicalTrials.gov

Recruiting · Not applicable

Efficacy of Gamma Auditory Stimulation for Cognitive Decline in Older Adults (Study 1)

Ages 60 Years to no maximum · 1 site · Chang Gung Memorial Hospital

NCT07087951 on ClinicalTrials.gov

Not yet recruiting · Phase 1

Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia

Ages 18 Years to 65 Years · 1 site · Nyree Penn

NCT06644573 on ClinicalTrials.gov

Recruiting · Not applicable

The Role of METhanogens in the PROgression Of Parkinson's Disease and Related Neurological Conditions

Ages 55 Years to no maximum · 1 site · University of Cambridge

NCT07786116 on ClinicalTrials.gov

Recruiting · Phase 2

Daridorexant to Prevent Post-cardiotomy Delirium

Ages 60 Years to no maximum · 1 site · University of Rochester

NCT07217912 on ClinicalTrials.gov

Recruiting · Not applicable

Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.

Ages 18 Years to no maximum · 1 site · University of Southern California

NCT06418971 on ClinicalTrials.gov

Recruiting · Not applicable

Evaluation of the Effectiveness of Virtual Reality Headsets With Hypnotic Scenarios for Hygiene Care in Patients With Alzheimer's Disease or Related Disorders With Behavioral Disturbances

Ages 18 Years to no maximum · 1 site · Centre Hospitalier Universitaire, Amiens

NCT07264439 on ClinicalTrials.gov

Recruiting · Not applicable

Mitochondrial Function and Metabolomic Profile in Alzheimer's Disease and Related Dementias

Ages 18 Years to no maximum · 1 site · Centre Hospitalier Universitaire de Nice

NCT06880406 on ClinicalTrials.gov

Recruiting · Not applicable

The BRAIN App (Phase 2 SBIR)

Ages 65 Years to no maximum · 1 site · Hopeful Aging

NCT06298474 on ClinicalTrials.gov

Recruiting · Phase 3

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Ages 18 Years to 75 Years · 104 sites · Eidos Therapeutics, a BridgeBio company

NCT06563895 on ClinicalTrials.gov

Recruiting · Not applicable

Feasibility of Using the Gatorade Sports Science Institute (GSSI) Labs App for Hydration Related Outcomes

Ages 18 Years to 65 Years · 1 site · PepsiCo Global R&D

NCT07005895 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Study to Detect Dendritic Cell Recruitment in Human Retina

Ages 55 Years to 80 Years · 0 sites · MindImmune Therapeutics, Inc.

NCT06872658 on ClinicalTrials.gov

Recruiting · Not applicable

VR Pupillometry in Cognitive Impairment

Ages 18 Years to 80 Years · 1 site · Max-Planck-Institute of Psychiatry

NCT07402356 on ClinicalTrials.gov

Recruiting · Not applicable

Feasibility and Interest of the 3D Ephemeris for Temporal Orientation in Alzheimer's: Pilot Study

Ages 65 Years to no maximum · 1 site · Assistance Publique - Hôpitaux de Paris

NCT06824142 on ClinicalTrials.gov

Recruiting · Not applicable

Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)

Ages 65 Years to no maximum · 3 sites · Istituto Nazionale di Ricovero e Cura per Anziani

NCT07435467 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

The DIAGNOSE CTE Research Project-II

Ages 50 Years to no maximum · 5 sites · Boston University

NCT06860828 on ClinicalTrials.gov

Recruiting · Not applicable

Connect-Home: Alzheimer's Disease and Related Dementias

Ages 19 Years to no maximum · 1 site · University of North Carolina, Chapel Hill

NCT06840587 on ClinicalTrials.gov

Recruiting · Not applicable

Development of Measures to Screen for Financial Hardship in Alzheimer's Disease and Dementia

Ages 18 Years to no maximum · 1 site · Fred Hutchinson Cancer Center

NCT06922188 on ClinicalTrials.gov

Recruiting · Not applicable

Early-Stage Partner in Care Living Alone Plus

Ages 60 Years to no maximum · 1 site · Arizona State University

NCT06962111 on ClinicalTrials.gov

Recruiting · Not applicable

Remote tDCS and Chair Yoga for Chronic Knee Pain in Alzheimer's Patients

Ages 60 Years to no maximum · 1 site · University of Arizona

NCT07303998 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs.

Ages 40 Years to no maximum · 1 site · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

NCT07234851 on ClinicalTrials.gov

Recruiting · Early Phase 1

[18F]ACI-19626 PET in TDP-43 Proteinopathies

Ages 40 Years to 70 Years · 1 site · AC Immune SA

NCT06891716 on ClinicalTrials.gov

Recruiting · Not applicable

Mindfulness to Enhance Cognitive Health in Latino Older Adults

Ages 65 Years to no maximum · 1 site · Washington University School of Medicine

NCT07040904 on ClinicalTrials.gov

Recruiting · Not applicable

Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults

Ages 50 Years to no maximum · 1 site · Universidade Federal do Rio de Janeiro

NCT06733714 on ClinicalTrials.gov

Recruiting · Phase 1

A Study of CM383 in Patients With Alzheimer's Disease Related Mild Cognitive Impairment and Mild Alzheimer's Disease

Ages 50 Years to 85 Years · 1 site · Keymed Biosciences Co.Ltd

NCT06619613 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA)

Ages 18 Years to no maximum · 5 sites · Winfried Meißner

NCT06604507 on ClinicalTrials.gov

Recruiting · Not applicable

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

Ages 60 Years to 90 Years · 23 sites · GAP Innovations, PBC

NCT06584357 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

Frailty Outcomes And Risk With Alzheimer's Related Dementia

Ages 65 Years to no maximum · 1 site · Aalborg University Hospital

NCT06570109 on ClinicalTrials.gov

Recruiting · Not applicable

Remote Sensing for ADRD-Specific Activities Identification in Older Adults

Ages 50 Years to no maximum · 1 site · University of Missouri-Columbia

NCT07120347 on ClinicalTrials.gov

Recruiting · Not applicable

Early Age-Related Hearing Loss Investigation (EARHLI)

Ages 55 Years to 75 Years · 1 site · Columbia University

NCT06174038 on ClinicalTrials.gov

Recruiting · Not applicable

OTC Hearing Aid and MCI

Ages 60 Years to 90 Years · 1 site · Northwestern University

NCT06112860 on ClinicalTrials.gov

Recruiting · Not applicable

The Peripheral Blood Multi-Omics Study on Sleep Loss

Ages 18 Years to 80 Years · 1 site · First Affiliated Hospital of Zhejiang University

NCT06492109 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife

Ages 30 Years to 70 Years · 1 site · Milton S. Hershey Medical Center

NCT05826379 on ClinicalTrials.gov

Recruiting · Not applicable

A Post Marketing Study in Participants With Early Alzheimer's Disease Treated With Lecanemab

Ages 18 Years to no maximum · 3 sites · Eisai Co., Ltd.

NCT06322667 on ClinicalTrials.gov

Recruiting · Not applicable

Premorbid Personality Profile of Patients With Cognitive and Behavioral Disorders

Ages 18 Years to no maximum · 1 site · Nantes University Hospital

NCT06059313 on ClinicalTrials.gov

Recruiting · Not applicable

Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's

Ages 60 Years to no maximum · 3 sites · Florida State University

NCT05748613 on ClinicalTrials.gov

Recruiting · Not applicable

Pan-Amyloid PET/CT in Various Amyloid-Related Disease

Ages 18 Years to 80 Years · 3 sites · Tianjin Medical University

NCT07130565 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

The Nightlight Falls Prevention Study

Ages 18 Years to no maximum · 1 site · University of North Carolina, Chapel Hill

NCT05973448 on ClinicalTrials.gov

Recruiting · Not applicable

Goal Setting to Promote Physical Activity Adherence in Midlife Adults

Ages 45 Years to 65 Years · 1 site · Arizona State University

NCT05980052 on ClinicalTrials.gov

Recruiting · Not applicable

I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms

Ages 18 Years to no maximum · 2 sites · Indiana University

NCT05733520 on ClinicalTrials.gov

Recruiting · Not applicable

Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1

Ages 50 Years to no maximum · 1 site · Washington University School of Medicine

NCT06129838 on ClinicalTrials.gov

Recruiting · Early Phase 1

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

Ages 40 Years to 99 Years · 1 site · Massachusetts General Hospital

NCT06538311 on ClinicalTrials.gov

Recruiting · Not applicable

Intervention to Collect and Utilize Sexual Orientation and Gender Identity (SOGI) Information in Hospice

Ages 18 Years to no maximum · 1 site · University of Colorado, Denver

NCT05877391 on ClinicalTrials.gov

Recruiting · Not applicable

Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons

Ages 18 Years to no maximum · 1 site · Kessler Foundation

NCT05048966 on ClinicalTrials.gov

Recruiting · Not applicable

NYSCF Scientific Discovery Biobank

Ages 30 Days to no maximum · 1 site · New York Stem Cell Foundation Research Institute

NCT06203106 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

Ages No minimum to no maximum · 27 sites · Marinella Temprosa

NCT05704309 on ClinicalTrials.gov

Recruiting · Not applicable

Natives Engaged in Alzheimers Research - 'Ike Kupuna

Ages 50 Years to 75 Years · 3 sites · University of Hawaii

NCT05534607 on ClinicalTrials.gov

Recruiting · Not applicable

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

Ages 18 Years to no maximum · 1 site · Johns Hopkins University

NCT05556395 on ClinicalTrials.gov

Recruiting · Phase 1 / Phase 2

Assess Fibrin in Brains With AD/ADRD

Ages 55 Years to 90 Years · 1 site · Massachusetts General Hospital

NCT05336695 on ClinicalTrials.gov

Recruiting · Not applicable

Moving Yourself in Space and Time: MYSTIC

Ages 18 Years to 79 Years · 1 site · Emory University

NCT07697664 on ClinicalTrials.gov

Recruiting · Not applicable

Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease

Ages 45 Years to 80 Years · 2 sites · Hôpital le Vinatier

NCT04946916 on ClinicalTrials.gov

Recruiting · Phase 2

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

Ages 18 Years to 55 Years · 1 site · Vanderbilt University Medical Center

NCT05231798 on ClinicalTrials.gov

Recruiting · Not applicable

Study on the Relationship Between Peripheral Blood miRNA and Risk and Severity of Alzheimer's Disease

Ages 65 Years to no maximum · 1 site · Jiajie Chen

NCT06442852 on ClinicalTrials.gov

Enrolling by invitation · Phase 2

Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia and Related Dementias

Ages 60 Years to no maximum · 1 site · Val Lowe

NCT04786223 on ClinicalTrials.gov

Recruiting · Not applicable

TAS Test: Online Motor-cognitive Tests for Early Detection of Alzheimer's Disease

Ages 50 Years to no maximum · 1 site · University of Tasmania

NCT05194787 on ClinicalTrials.gov

Recruiting · Phase 3

Nabilone for Agitation Blinded Intervention Trial

Ages 55 Years to no maximum · 6 sites · Sunnybrook Health Sciences Centre

NCT04516057 on ClinicalTrials.gov

Recruiting · Not applicable

MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics

Ages 18 Years to no maximum · 1 site · Mayo Clinic

NCT04099823 on ClinicalTrials.gov

Recruiting · Not applicable

Retinal Imaging in Neurodegenerative Disease

Ages 18 Years to no maximum · 1 site · Duke University

NCT03233646 on ClinicalTrials.gov

Recruiting · Not applicable

Aerobic Exercise for Older Adults at Increased Risk of Alzheimer's Disease and Related Dementias

Ages 50 Years to 80 Years · 1 site · University of Calgary

NCT03035851 on ClinicalTrials.gov

Recruiting · Not applicable

Motor Slowing and Its Lesion-related Correlates in Alzheimer's Disease

Ages 40 Years to 85 Years · 1 site · Centre Hospitalier Universitaire, Amiens

NCT02811653 on ClinicalTrials.gov

Recruiting · Not applicable

Predictive Factors and Autonomy Level Change

Ages 65 Years to no maximum · 2 sites · Hospices Civils de Lyon

NCT02302482 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

Brain Health Registry: An Online Registry to Identify and Assess Subjects for Brain Research

Ages 18 Years to no maximum · 1 site · University of California, San Francisco

NCT02402426 on ClinicalTrials.gov

Recruiting · Not applicable

Beta Amyloid PET/CT in Various Aβ-Related Disease

Ages 18 Years to 80 Years · 4 sites · Tianjin Medical University

NCT06725706 on ClinicalTrials.gov

Recruiting · Not applicable

Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases

Ages 18 Years to no maximum · 1 site · Hadassah Medical Organization

NCT00874783 on ClinicalTrials.gov

Recruiting · Not applicable

Alzheimer's Disease Genetics Study

Ages 18 Years to no maximum · 1 site · Indiana University

NCT00064870 on ClinicalTrials.gov