Depression clinical trials in California

Mental health

Also: Texas

160 trials are recruiting in California, according to ClinicalTrials.gov.

Showing 100 of 160, newest first. Checked against the registry on 23 October 2026. Listing a trial here is not a recommendation; taking part is voluntary and each study team decides who is eligible.

Recruiting · Phase 2 · Listed on Beacon

Study of ALTO-300 in MDD

Ages 18 Years to 70 Years · 38 sites · in California: Bellflower, Glendale, Lafayette, Los Angeles, Mather, Mission Viejo · Alto Neuroscience

Details and how to check if you qualify · NCT05922878 on ClinicalTrials.gov

Recruiting · Phase 3 · Listed on Beacon

A Study to Evaluate the Maintenance Effect of Osavampator as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Ages 18 Years to no maximum · 55 sites · in California: Oceanside, Orange, San Jose · Neurocrine Biosciences

Details and how to check if you qualify · NCT07196501 on ClinicalTrials.gov

Recruiting · Phase 2 · Listed on Beacon

Mindfulness Engaged Neurostimulation for Depression (MEND II)

Ages 18 Years to 65 Years · 1 site · in California: San Diego · University of California, San Diego

Details and how to check if you qualify · NCT07512284 on ClinicalTrials.gov

Recruiting · Phase 2 · Listed on Beacon

A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

Ages 18 Years to 75 Years · 40 sites · in California: Oceanside, San Diego, Torrance · Draig Therapeutics Ltd

Details and how to check if you qualify · NCT07300969 on ClinicalTrials.gov

Not yet recruiting · Not applicable

A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms

Ages 18 Years to no maximum · 1 site · in California: Palo Alto · VA Office of Research and Development

NCT06689787 on ClinicalTrials.gov

Not yet recruiting · Phase 1 / Phase 2

A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients

Ages 21 Years to 85 Years · 1 site · in California: Los Angeles · BioLite, Inc.

NCT03833206 on ClinicalTrials.gov

Not yet recruiting · Phase 2

Group PACBT for Depression

Ages 21 Years to 60 Years · 1 site · in California: Los Angeles · University of California, Los Angeles

NCT07566104 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Multi-site Feasibility of an Integrated Treatment for the Biology and Experience of Depression: The MULTIBED Study

Ages 18 Years to no maximum · 3 sites · in California: San Francisco · University of California, San Francisco

NCT07596914 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings

Ages 11 Years to 17 Years · 1 site · in California: Los Angeles · Children's Hospital Los Angeles

NCT07755137 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Sham-Controlled Rapid-Acting Neuromodulation for Depression

Ages 18 Years to 65 Years · 1 site · in California: Sacramento · University of California, Davis

NCT07487454 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Development of Low-Intensity Focused Ultrasound for Post Traumatic Brain Injury Depression

Ages 22 Years to 55 Years · 1 site · in California: Stanford · Stanford University

NCT07828483 on ClinicalTrials.gov

Not yet recruiting · Phase 2

A Study to Evaluate BMS-986511 in Adults With Major Depressive Disorder

Ages 18 Years to 65 Years · 27 sites · in California: Garden Grove, Glendale, Lemon Grove, Oakland, Upland · Bristol-Myers Squibb

NCT07772531 on ClinicalTrials.gov

Recruiting · Phase 3

Morphine or Ketamine for Analgesia

Ages 6 Years to 17 Years · 8 sites · in California: Los Angeles, Sacramento · Columbia University

NCT06835504 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Home-Based Randomized Trial of Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression

Ages 18 Years to 70 Years · 1 site · in California: San Diego · University of California, San Diego

NCT07834762 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Sensory Synchronized Imaging and Neuromodulation

Ages 18 Years to no maximum · 1 site · in California: Palo Alto · VA Office of Research and Development

NCT06548113 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Focused Ultrasound for Behavioral Health

Ages 22 Years to 80 Years · 1 site · in California: San Francisco · Attune Neurosciences Inc

NCT07851038 on ClinicalTrials.gov

Recruiting · Not applicable

SAINT® Therapy for Memory Problems in Older Adults With Treatment-Resistant Depression

Ages 65 Years to no maximum · 1 site · in California: Costa Mesa · BrainHealth Solutions, Inc.

NCT07876908 on ClinicalTrials.gov

Recruiting · Phase 3

Brexanolone Lifting Outcomes Of Moms

Ages 15 Years to 45 Years · 16 sites · in California: Canoga Park, Walnut Creek · Lipocine Inc.

NCT07822321 on ClinicalTrials.gov

Recruiting · Not applicable

An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being

Ages 18 Years to no maximum · 2 sites · in California: San Diego, San Diego · San Diego State University

NCT07792837 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Supported Online Self-Help for Veterans With Depression in Primary Care

Ages 18 Years to no maximum · 2 sites · in California: San Diego, West Los Angeles · University of California, Los Angeles

NCT07781228 on ClinicalTrials.gov

Recruiting · Phase 3

A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder

Ages 18 Years to 75 Years · 170 sites · in California: Irvine, Long Beach, Oakland, Valley Village · Eli Lilly and Company

NCT07775300 on ClinicalTrials.gov

Recruiting · Not applicable

Enhancing Veteran-Clinical Collaboration in VA PRRCs

Ages 18 Years to no maximum · 3 sites · in California: San Diego, West Los Angeles · VA Office of Research and Development

NCT06898879 on ClinicalTrials.gov

Recruiting · Phase 3

A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

Ages 18 Years to no maximum · 22 sites · in California: Redlands, San Diego · Janssen Research & Development, LLC

NCT07716098 on ClinicalTrials.gov

Recruiting · Not applicable

Supporting Mental Health and Reducing Care Stress in Caregivers of Persons With Cardiovascular Disease

Ages 18 Years to no maximum · 1 site · in California: Sacramento · University of California, Davis

NCT07717723 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Debriefing Consult for Psychiatric Symptoms After Severe Maternal Morbidity

Ages 18 Years to no maximum · 1 site · in California: Los Angeles · Cedars-Sinai Medical Center

NCT07684521 on ClinicalTrials.gov

Not yet recruiting · Phase 2

Study of Psilocybin Under Anesthesia Controlled by EEG

Ages 25 Years to 65 Years · 1 site · in California: Stanford · Stanford University

NCT07479550 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Neuronavigated aiTBS for TRD

Ages 18 Years to 65 Years · 3 sites · in California: San Diego · University of Texas Southwestern Medical Center

NCT07329153 on ClinicalTrials.gov

Recruiting · Phase 2

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

Ages 18 Years to no maximum · 26 sites · in California: Buena Park, Chino, Lemon Grove, Orange, San Diego, Walnut Creek · Tonix Pharmaceuticals, Inc.

NCT07621237 on ClinicalTrials.gov

Recruiting · Not applicable

Phase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings

Ages 5 Years to 14 Years · 2 sites · in California: Monterey, Stanford · Stanford University

NCT07155707 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Calming Minds Study

Ages 18 Years to no maximum · 1 site · in California: Imperial · University of California, Los Angeles

NCT07577401 on ClinicalTrials.gov

Recruiting · Early Phase 1

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

Ages 50 Years to 95 Years · 1 site · in California: Los Angeles · University of California, Los Angeles

NCT06906939 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Early Brainwave Biomarkers for Personalized Neuromodulation in Treatment-resistant Depression

Ages 18 Years to 65 Years · 1 site · in California: Stanford · Stanford University

NCT07528157 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 3)

Ages 18 Years to no maximum · 1 site · in California: San Diego · San Diego State University

NCT07010133 on ClinicalTrials.gov

Recruiting · Not applicable

CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life

Ages 18 Years to 65 Years · 1 site · in California: San Francisco · Samphire Group, Inc.

NCT07679074 on ClinicalTrials.gov

Recruiting · Not applicable

Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 2)

Ages 18 Years to no maximum · 1 site · in California: San Diego · San Diego State University

NCT06753123 on ClinicalTrials.gov

Recruiting · Phase 2

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

Ages 18 Years to 75 Years · 23 sites · in California: Bellflower, Costa Mesa, Lafayette · Draig Therapeutics Ltd

NCT07610473 on ClinicalTrials.gov

Recruiting · Phase 3

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

Ages 18 Years to 74 Years · 28 sites · in California: Orange, San Diego, San Francisco, Santa Monica · Definium Therapeutics US, Inc.

NCT07592689 on ClinicalTrials.gov

Recruiting · Not applicable

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

Ages 3 Years to 17 Years · 2 sites · in California: San Francisco · NeurOptics Inc

NCT07573150 on ClinicalTrials.gov

Recruiting · Not applicable

Health And Response: Digital Markers for Outcomes in Perinatal Depression Treatment Study

Ages 18 Years to no maximum · 1 site · in California: Los Angeles · University of California, Los Angeles

NCT07577947 on ClinicalTrials.gov

Recruiting · Phase 2

ALTO-207 in Adults With Treatment-resistant Depression (TRD)

Ages 18 Years to 75 Years · 48 sites · in California: Chino, Oakland, Oceanside, Palo Alto, Sacramento, San Diego · Alto Neuroscience

NCT07553637 on ClinicalTrials.gov

Recruiting · Phase 3

A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

Ages 18 Years to 74 Years · 45 sites · in California: Bellflower, Glendale, Oceanside, Orange, Riverside, Walnut Creek · Janssen Research & Development, LLC

NCT07573176 on ClinicalTrials.gov

Recruiting · Not applicable

Cognition and Behavior With Sham Accelerated TMS

Ages 15 Years to 25 Years · 1 site · in California: Sacramento · University of California, Davis

NCT07397858 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

Virtual Reality-enhanced Psychotherapy for Perinatal Depression

Ages 18 Years to no maximum · 1 site · in California: Palo Alto · Stanford University

NCT07279311 on ClinicalTrials.gov

Recruiting · Phase 2

Sleep Health in U.S. Marines

Ages 18 Years to no maximum · 1 site · in California: San Diego · San Diego State University

NCT07420205 on ClinicalTrials.gov

Recruiting · Not applicable

ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1

Ages 18 Years to no maximum · 2 sites · in California: La Jolla, Laguna Hills · Salma Health, Inc.

NCT07528014 on ClinicalTrials.gov

Recruiting · Phase 2

ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression

Ages 18 Years to 60 Years · 2 sites · in California: Palo Alto · Stanford University

NCT06408246 on ClinicalTrials.gov

Recruiting · Phase 2

Ketamine for Veterans With Parkinson's Disease

Ages 40 Years to 80 Years · 1 site · in California: San Francisco · VA Office of Research and Development

NCT06231563 on ClinicalTrials.gov

Recruiting · Not applicable

Nutritional Intervention for College Students With Depression

Ages 18 Years to no maximum · 1 site · in California: La Jolla · University of California, San Diego

NCT07490782 on ClinicalTrials.gov

Recruiting · Phase 3

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

Ages 18 Years to 65 Years · 40 sites · in California: Bellflower, Chino, Glendale, Imperial, Los Angeles, Oceanside · Axsome Therapeutics, Inc.

NCT07484217 on ClinicalTrials.gov

Recruiting · Phase 3

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

Ages 18 Years to 75 Years · 179 sites · in California: Moorpark, Orange · Eli Lilly and Company

NCT07412756 on ClinicalTrials.gov

Recruiting · Phase 2

A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

Ages 18 Years to 65 Years · 33 sites · in California: Anaheim, Garden Grove, Montclair, Oceanside, Orange, Sherman Oaks · AbbVie

NCT06696755 on ClinicalTrials.gov

Recruiting · Not applicable

Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth

Ages 12 Years to 18 Years · 1 site · in California: San Luis Obispo · SoundHeal

NCT07364799 on ClinicalTrials.gov

Recruiting · Phase 2

Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.

Ages 18 Years to 65 Years · 26 sites · in California: Bellflower, Culver City, Garden Grove, Lemon Grove, Los Angeles, Orange · LB Pharmaceuticals Inc.

NCT07494305 on ClinicalTrials.gov

Recruiting · Phase 2

Stratified Pharmacological Approaches for Regulating Circuit-Level Effects

Ages 18 Years to 65 Years · 1 site · in California: Palo Alto · Stanford University

NCT07022405 on ClinicalTrials.gov

Recruiting · Phase 2

Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder

Ages 18 Years to 70 Years · 1 site · in California: Garden Grove · Supernus Pharmaceuticals, Inc.

NCT07226661 on ClinicalTrials.gov

Enrolling by invitation · Not applicable

NQ Square TMS for MDD 1Dx3S Adults Multi-site Sham-controlled Protocol

Ages 22 Years to 85 Years · 2 sites · in California: Campbell, Sunnyvale · NeuroQore Inc.

NCT07369180 on ClinicalTrials.gov

Recruiting · Not applicable

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial

Ages 18 Years to no maximum · 1 site · in California: La Jolla · University of California, San Diego

NCT07223736 on ClinicalTrials.gov

Recruiting · Phase 2

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Ages 18 Years to 64 Years · 30 sites · in California: Montclair, Oceanside, Redlands, San Francisco, San Jose, Walnut Creek · Syndeio Biosciences, Inc

NCT07115329 on ClinicalTrials.gov

Recruiting · Phase 1 / Phase 2

RCT of Psilocybin-assisted CBT for Depression

Ages 21 Years to 60 Years · 1 site · in California: Los Angeles · University of California, Los Angeles

NCT07281352 on ClinicalTrials.gov

Recruiting · Phase 2

A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

Ages 18 Years to 65 Years · 33 sites · in California: Anaheim, Imperial, Lemon Grove, Long Beach, Sherman Oaks, Temecula · AbbVie

NCT07276997 on ClinicalTrials.gov

Recruiting · Phase 3

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

Ages 18 Years to 85 Years · 68 sites · in California: Glendale, Los Angeles, Los Angeles, Orange, Orange, San Juan Capistrano · Cybin IRL Limited

NCT06793397 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Living Well Program: Impact on Healthcare Costs and Clinical Outcomes in Breast Cancer Care

Ages 18 Years to no maximum · 1 site · in California: Los Angeles · Scott A. Irwin, MD, PhD

NCT07236437 on ClinicalTrials.gov

Recruiting · Phase 2

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

Ages 18 Years to 65 Years · 24 sites · in California: Chino, Glendale, La Jolla, Orange, West Hills · ACADIA Pharmaceuticals Inc.

NCT07284667 on ClinicalTrials.gov

Recruiting · Not applicable

Optimizing Brain Excitability in Depression

Ages 18 Years to 65 Years · 2 sites · in California: Iowa City, Stanford · Stanford University

NCT07242105 on ClinicalTrials.gov

Not yet recruiting · Phase 2

A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder

Ages 21 Years to 65 Years · 1 site · in California: Los Angeles · Afasci Inc

NCT06710431 on ClinicalTrials.gov

Recruiting · Not applicable

Virtual Reality-Enhanced Behavioral Activation for Older Adults With Depression

Ages 65 Years to no maximum · 1 site · in California: Stanford · Stanford University

NCT07188623 on ClinicalTrials.gov

Recruiting · Not applicable

Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study

Ages 18 Years to 85 Years · 1 site · in California: San Diego · University of California, San Diego

NCT07217223 on ClinicalTrials.gov

Enrolling by invitation · Phase 2

An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)

Ages 18 Years to 66 Years · 42 sites · in California: Chino, Garden Grove, Glendale, San Jose · Seaport Therapeutics

NCT07161700 on ClinicalTrials.gov

Recruiting · Phase 4

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

Ages 18 Years to no maximum · 19 sites · in California: Chino, Fresno, Long Beach, Orange, Redlands, San Diego · Neurocrine Biosciences

NCT07105111 on ClinicalTrials.gov

Recruiting · Not applicable

SUpport From PEeRs to Expand Access Study - Community

Ages 18 Years to 100 Years · 1 site · in California: San Francisco · University of California, Berkeley

NCT07186816 on ClinicalTrials.gov

Recruiting · Not applicable

fMRI Neurofeedback With Matter Neuroscience App

Ages 18 Years to 80 Years · 1 site · in California: Stanford · Stanford University

NCT06735885 on ClinicalTrials.gov

Recruiting · Phase 2

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

Ages 18 Years to 80 Years · 32 sites · in California: San Diego, Santa Rosa · Reunion Neuroscience Inc

NCT07002034 on ClinicalTrials.gov

Enrolling by invitation · Phase 3

Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)

Ages 18 Years to 85 Years · 49 sites · in California: Glendale, La Jolla, Los Angeles, Los Angeles, Los Angeles, Oceanside · Cybin IRL Limited

NCT06605105 on ClinicalTrials.gov

Recruiting · Not applicable

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

Ages 22 Years to 70 Years · 1 site · in California: San Francisco · Andrew Krystal

NCT07127913 on ClinicalTrials.gov

Recruiting · Not applicable

HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

Ages 18 Years to no maximum · 4 sites · in California: Los Angeles · Children's Hospital Medical Center, Cincinnati

NCT06175104 on ClinicalTrials.gov

Recruiting · Not applicable

RCT for Latina Mental Health Using Web-Based Apps

Ages 18 Years to no maximum · 1 site · in California: Los Angeles · University of California, Los Angeles

NCT06874790 on ClinicalTrials.gov

Recruiting · Not applicable

Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk

Ages 15 Years to 25 Years · 1 site · in California: Sacramento · University of California, Davis

NCT07025720 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic Profiling

Ages 18 Years to 80 Years · 1 site · in California: Palo Alto · Stanford University

NCT06748950 on ClinicalTrials.gov

Recruiting · Phase 3

E-Mindfulness Approaches for Living After Breast Cancer

Ages 18 Years to 50 Years · 376 sites · in California: Anaheim, Antioch, Bakersfield, Baldwin Park, Bellflower, Cameron Park · NRG Oncology

NCT06748222 on ClinicalTrials.gov

Recruiting · Not applicable

Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers

Ages 18 Years to no maximum · 1 site · in California: Duarte · City of Hope Medical Center

NCT06985784 on ClinicalTrials.gov

Recruiting · Phase 2

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

Ages 18 Years to 65 Years · 55 sites · in California: Chino, Garden Grove, Glendale, Redlands, San Jose · Seaport Therapeutics

NCT07065240 on ClinicalTrials.gov

Enrolling by invitation · Phase 2

Ketamine Effects on Learning In Eating Disorders

Ages 16 Years to 26 Years · 1 site · in California: San Francisco · Amanda Downey, MD

NCT06736769 on ClinicalTrials.gov

Recruiting · Not applicable

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

Ages 18 Months to 11 Years · 12 sites · in California: Orange · State University of New York at Buffalo

NCT07048574 on ClinicalTrials.gov

Recruiting · Phase 3

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Ages 18 Years to no maximum · 28 sites · in California: Chino, Los Angeles, Stanford · Neurocrine Biosciences

NCT06963021 on ClinicalTrials.gov

Recruiting · Not applicable

Improving Behavioral Health for Caregivers and Children After Pediatric Injury

Ages 18 Years to no maximum · 4 sites · in California: Los Angeles · Medical University of South Carolina

NCT06856057 on ClinicalTrials.gov

Recruiting · Phase 2

Training Reward Responsiveness Through Virtual Reality

Ages 18 Years to no maximum · 1 site · in California: Los Angeles · University of California, Los Angeles

NCT07219875 on ClinicalTrials.gov

Enrolling by invitation · Phase 1

Induction of Dreaming With EEG and Anesthesia in Healthy Adults

Ages 18 Years to 70 Years · 1 site · in California: Stanford · Stanford University

NCT07198711 on ClinicalTrials.gov

Recruiting · Not applicable

Assessing Improvements in Mood and Sleep Trial

Ages 55 Years to no maximum · 3 sites · in California: Los Angeles · University of Pittsburgh

NCT06639477 on ClinicalTrials.gov

Recruiting · Early Phase 1

Probiotic Administration for Adolescent Depression

Ages 15 Years to 24 Years · 1 site · in California: San Francisco · University of California, San Francisco

NCT06898788 on ClinicalTrials.gov

Recruiting · Not applicable

Sleep TMS for Depression

Ages 18 Years to 65 Years · 1 site · in California: Stanford · Stanford University

NCT06824415 on ClinicalTrials.gov

Recruiting · Phase 3

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Ages 18 Years to no maximum · 97 sites · in California: Glendale, Los Angeles, Oceanside, Orange, Pico Rivera, San Diego · Neurocrine Biosciences

NCT06966401 on ClinicalTrials.gov

Recruiting · Not applicable

Filipino Family Health Initiative 1.0

Ages 8 Years to no maximum · 1 site · in California: Pasadena · Kaiser Permanente

NCT06569303 on ClinicalTrials.gov

Recruiting · Phase 1 / Phase 2

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

Ages 14 Years to 21 Years · 1 site · in California: Los Angeles · Children's Hospital Los Angeles

NCT05685368 on ClinicalTrials.gov

Recruiting · Not applicable

In-patient SCC TMS

Ages 18 Years to 65 Years · 1 site · in California: Los Angeles · University of California, Los Angeles

NCT05645575 on ClinicalTrials.gov

Recruiting · Not applicable

Maintenance rTMS for Depression (Maitr-De)

Ages 18 Years to 80 Years · 3 sites · in California: San Diego · University of California, San Diego

NCT06938841 on ClinicalTrials.gov

Not yet recruiting · Not applicable

Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)

Ages 18 Years to 80 Years · 2 sites · in California: San Diego · Neurovalens Ltd.

NCT06470035 on ClinicalTrials.gov

Recruiting · Phase 3

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Ages 18 Years to no maximum · 34 sites · in California: Glendale, Redlands, San Francisco · Neurocrine Biosciences

NCT06911112 on ClinicalTrials.gov

Recruiting · Not applicable

Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction

Ages 45 Years to 75 Years · 1 site · in California: San Diego · University of California, San Diego

NCT06678880 on ClinicalTrials.gov

Recruiting · Phase 3

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

Ages 18 Years to 65 Years · 50 sites · in California: Garden Grove, Orange, Redlands, San Jose, Walnut Creek · Vanda Pharmaceuticals

NCT06830044 on ClinicalTrials.gov

Recruiting · Not applicable

The Impact of Melatonin Lotion on Sleep and Mental Health

Ages 18 Years to 21 Years · 1 site · in California: Redlands · University of Redlands

NCT06768749 on ClinicalTrials.gov

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